Molecular genetics and targeted therapy of WNT-related human diseases (Review)
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چکیده
منابع مشابه
Molecular genetics and targeted therapy of WNT-related human diseases (Review)
Canonical WNT signaling through Frizzled and LRP5/6 receptors is transduced to the WNT/β-catenin and WNT/stabilization of proteins (STOP) signaling cascades to regulate cell fate and proliferation, whereas non-canonical WNT signaling through Frizzled or ROR receptors is transduced to the WNT/planar cell polarity (PCP), WNT/G protein-coupled receptor (GPCR) and WNT/receptor tyrosine kinase (RTK)...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2017
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.2017.3071